Benzylamine → HCID 68577135, compound

HRID 1949029Notes

Reaction equation

HRID 1949029 reaction equation
Br[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9](Cl)[CH:10]=2)[N:5]=[C:4]([NH:13][CH2:14][C:15]2[CH:20]=[CH:19][C:18]([F:21])=[CH:17][C:16]=2[O:22][CH3:23])[CH:3]=1.[CH3:24][O:25][CH2:26][CH2:27][NH2:28].[CH2:29]([NH2:36])[C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1>>[CH2:29]([NH:36][C:9]1[CH:10]=[C:11]2[C:6](=[CH:7][CH:8]=1)[N:5]=[C:4]([NH:13][CH2:14][C:15]1[CH:20]=[CH:19][C:18]([F:21])=[CH:17][C:16]=1[O:22][CH3:23])[CH:3]=[C:2]2[NH:28][CH2:27][CH2:26][O:25][CH3:24])[C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1

Participants

4

Reactant 3

HCID 7504BenzylamineHCID 80182-MethoxyethylamineHCID 68574873HCID 68574873, compound

Product 1

HCID 68577135HCID 68577135, compound

Procedure

The title compound, MS: m/e=461.1 (M+H+), was prepared in accordance with the general method of example 40 from (4-bromo-6-chloro-quinolin-2-yl)-(4-fluoro-2-methoxy-benzyl)-amine, methoxyethylamine and benzylamine.

Sources & evidence

ORD record
ord-bf1500a9b4d540358eddcd61463bb00d
Source dataset
uspto-grants-2013_03
Patent number
US08399674B2

Reaction notes

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