2-Amino-6-methylpyridine → HCID 25235756, compound

HRID 1949070Notes

Reaction equation

HRID 1949070 reaction equation
Br[C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([NH:12][C:13]1[C:21]3[O:20][C:19]([CH3:23])([CH3:22])[CH2:18][C:17]=3[CH:16]=[CH:15][CH:14]=1)[CH:6]=[CH:5]2.[NH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[C:27]([CH3:31])[N:26]=1>>[CH3:22][C:19]1([CH3:23])[CH2:18][C:17]2[CH:16]=[CH:15][CH:14]=[C:13]([NH:12][C:7]3[CH:6]=[CH:5][C:4]4[C:9](=[CH:10][CH:11]=[C:2]([NH:24][C:25]5[CH:30]=[CH:29][CH:28]=[C:27]([CH3:31])[N:26]=5)[CH:3]=4)[N:8]=3)[C:21]=2[O:20]1

Participants

3

Reactant 2

HCID 157652-Amino-6-methylpyridineHCID 68574332HCID 68574332, compound

Product 1

HCID 25235756HCID 25235756, compound

Procedure

The title compound, yellow foam, MS: m/e=397.2 (M+H+), was prepared in accordance with the general method of example 84 from (6-bromo-quinolin-2-yl)-(2,2-dimethyl-2,3-dihydro-benzofuran-7-yl)-amine and commercially available 2-amino-6-methyl-pyridine.

Sources & evidence

ORD record
ord-85fb318ec1bc4fb587c29fce423cfa74
Source dataset
uspto-grants-2013_03
Patent number
US08399674B2

Reaction notes

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