HCID 50913954, compound → HCID 58129390, compound

Participants

Reaction Steps

A mixture of 33 mg (0.09 mmol) 1-benzyl-4-hydroxy-piperidine-4-carboxylic acid (4-isopropyl-phenyl)-amide in 15 mL ethanol and 10 uL acetic acid was hydrogenated over Pd/C with 1 bar H2 for 2 h at room temperature. The mixture was filtered, the catalyst washed with ethanol and the filtrate evaporated to dryness yielding 33 mg (70% purity) of the title compound. MS (m/e): 263.1 [(M+H)+].

Provenance & Evidence