Ethanol → Tert-butyl 4-(4-(4-aminophenyl)-6-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)-1,3,5-triazin-2-yl)piperazine-1-carboxylate
Reaction equation
[CH2:46]([OH:47])[CH3:48].[CH:1]12[CH2:2][N:3]([c:9]3[n:10][c:11]([N:16]4[CH2:17][CH2:18][N:19]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:20][CH2:21]4)[n:12][c:13]([Cl:15])[n:14]3)[CH2:4][CH:5]([CH2:6][CH2:7]1)[O:8]2.[NH2:29][c:30]1[cH:31][cH:32][c:33]([B:36]([OH:37])[OH:38])[cH:34][cH:35]1.[Na+:49].[Na+:50].[O-:51][C:52](=[O:53])[O-:54].[Pd:55].[c:113]1([P:114]([c:115]2[cH:116][cH:117][cH:118][cH:119][cH:120]2)[c:121]2[cH:122][cH:123][cH:124][cH:125][cH:126]2)[cH:127][cH:128][cH:129][cH:130][cH:131]1.[c:39]1([CH3:40])[cH:41][cH:42][cH:43][cH:44][cH:45]1.[c:56]1([P:57]([c:58]2[cH:59][cH:60][cH:61][cH:62][cH:63]2)[c:64]2[cH:65][cH:66][cH:67][cH:68][cH:69]2)[cH:70][cH:71][cH:72][cH:73][cH:74]1.[c:75]1([P:76]([c:77]2[cH:78][cH:79][cH:80][cH:81][cH:82]2)[c:83]2[cH:84][cH:85][cH:86][cH:87][cH:88]2)[cH:89][cH:90][cH:91][cH:92][cH:93]1.[c:94]1([P:95]([c:96]2[cH:97][cH:98][cH:99][cH:100][cH:101]2)[c:102]2[cH:103][cH:104][cH:105][cH:106][cH:107]2)[cH:108][cH:109][cH:110][cH:111][cH:112]1>>[CH:1]12[CH2:2][N:3]([c:9]3[n:10][c:11]([N:16]4[CH2:17][CH2:18][N:19]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:20][CH2:21]4)[n:12][c:13](-[c:33]4[cH:32][cH:31][c:30]([NH2:29])[cH:35][cH:34]4)[n:14]3)[CH2:4][CH:5]([CH2:6][CH2:7]1)[O:8]2Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-03454203f1074c37861d6cba4418b733
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…