HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Amino-2-methylpropoxy)-3-fluorobenzonitrile → Tert-butyl[2-(2-fluoro-4-formylphenoxy)-1,1-dimethylethyl]carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Amino-2-methylpropoxy)-3-fluorobenzonitrile | HCID 23087234 | — |
| Reactant | Tert-butyl [2-(4-cyano-2-fluorophenoxy)-1,1-dimethylethyl]carbamate | HCID 86605237 | — |
| Product | Tert-butyl[2-(2-fluoro-4-formylphenoxy)-1,1-dimethylethyl]carbamate | HCID 57934591 | — |
Reaction Steps
Synthesized from 4-(2-amino-2-methylpropoxy)-3-fluorobenzonitrile according to an analogous synthetic method to Preparation Example 19, tert-butyl[2-(4-cyano-2-fluorophenoxy)-1,1-dimethylethyl]carbamate (1.0 g) was used according to an analogous synthetic method to Preparation Example 20 to provide the title compound (715 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399520B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-f4e3d75a04574e4ba61a45bf727d7932 |
| Source note | uspto-grants-2013_03 |