HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Piperidinol, 1-methyl- → HCID 23087228, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Piperidinol, 1-methyl- | HCID 66048 | — |
| Reactant | 3,4-Difluorobenzonitrile | HCID 587203 | — |
| Reactant | 3-Fluoro-4-(1-methylpiperidin-4-yloxy)benzonitrile | HCID 23087412 | — |
| Product | HCID 23087228 | HCID 23087228 | — |
Reaction Steps
Synthesized from 4-hydroxy-1-methylpiperidine and 3,4-difluorobenzonitrile according to an analogous synthetic method to Preparation Example 15, 3-fluoro-4-(1-methylpiperidin-4-yloxy)benzonitrile (1.1 g) was used according to an analogous synthetic method to Preparation Example 16 to provide the title compound (1.1 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08399520B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-5180b8cb5d5d4ddfaf4ff088581d6be1 |
| Source note | uspto-grants-2013_03 |