1-Bromo-2-nitrobenzene → 7-Methoxy-3-(2-nitrophenyl)-1,2-dihydronaphthalene

HRID 1950050Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1950050
Br[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N+:8]([O-:10])=[O:9].C([Sn](CCCC)(CCCC)C1C=CC=CC=1[N+]([O-])=O)CCC.FC(F)(F)S(O[C:39]1[CH2:48][CH2:47][C:46]2[C:41](=[CH:42][CH:43]=[C:44]([O:49][CH3:50])[CH:45]=2)[CH:40]=1)(=O)=O>>[CH3:50][O:49][C:44]1[CH:45]=[C:46]2[C:41]([CH:40]=[C:39]([C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=3[N+:8]([O-:10])=[O:9])[CH2:48][CH2:47]2)=[CH:42][CH:43]=1

Komponenten

4

Edukt 3

HCID 113411-Bromo-2-nitrobenzeneHCID 11338886Stannane, tributyl(2-nitrophenyl)-HCID 153302566-Methoxy-3,4-dihydronaphthalen-2-yl trifluoromethanesulfonate

Produkt 1

HCID 230871487-Methoxy-3-(2-nitrophenyl)-1,2-dihydronaphthalene

Versuchsvorschrift

Synthesized from 1-bromo-2-nitrobenzene according to an analogous synthetic method to Preparation Example 76, tributyl(2-nitrophenyl)tin (7.3 g) and 6-methoxy-3,4-dihydronaphthalen-2-yl trifluoromethanesulfonate (2.2 g) were used according to an analogous synthetic method to Preparation Example 77 to provide the title compound (1.5 g).

Aufarbeitung

  1. customwere used according to an analogous synthetic method to Preparation Example 77

Quellen und Nachweise

ORD-Eintrag
ord-076b8ff06e8643a09f2a5fa280dc557f
Quelldatensatz
uspto-grants-2013_03
Patentnummer
US08399520B2

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