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4-Bromo-3-nitroanisole → 5-Methoxy-2-(6-methoxy-3,3-dimethyl-3,4-dihydronaphthalen-2-yl)phenylamine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Bromo-3-nitroanisole | HCID 79288 | — |
| 反応物 | 7-Methoxy-3-(4-methoxy-2-nitrophenyl)-2,2-dimethyl-1,2-dihydronaphthalene | HCID 23087432 | — |
| 反応物 | 3-Bromo-7-methoxy-2,2-dimethyl-1,2-dihydronaphthalene | HCID 23087570 | — |
| 生成物 | 5-Methoxy-2-(6-methoxy-3,3-dimethyl-3,4-dihydronaphthalen-2-yl)phenylamine | HCID 23087320 | 75.1% |
反応手順
Synthesized from 3-bromo-7-methoxy-2,2-dimethyl-1,2-dihydronaphthalene and 4-bromo-3-nitroanisole according to an analogous synthetic method to Preparation Example 107 described below, 7-methoxy-3-(4-methoxy-2-nitrophenyl)-2,2-dimethyl-1,2-dihydronaphthalene (1.9 g) was used according to an analogous synthetic method to Example 57 to provide the title compound (1.3 g).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08399520B2 |
| 出典データセット | uspto-grants-2013_03 |
| ORD ID | ord-36cec00b0b904a60890b7136475fad9b |
| 出典メモ | uspto-grants-2013_03 |