Dimethylamine → 2-(7-(dicyclopropylcarbamoyl)-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-4-ylamino)-N,N,5-trimethylthiazole-4-carboxamide

HRID 195051Notes

Reaction equation

HRID 195051 reaction equation
[CH3:35][NH:36][CH3:37].[CH:1]1([N:4]([C:5](=[O:6])[c:7]2[cH:8][c:9]3[c:10]([n:11][c:12]([NH:19][c:20]4[s:21][c:22]([CH3:28])[c:23]([C:25](=[O:26])[OH:27])[n:24]4)[c:13]4[c:14]3[n:15]([CH3:18])[cH:16][n:17]4)[n:29]2[CH2:30][CH3:31])[CH:32]2[CH2:33][CH2:34]2)[CH2:2][CH2:3]1.[O:62]=[CH:63][N:64]([CH3:65])[CH3:66].[P-:38]([F:39])([F:40])([F:41])([F:42])([F:43])[F:44].[n:45]1([O:46][C:47]([N:48]([CH3:49])[CH3:50])=[N+:51]([CH3:52])[CH3:53])[c:54]2[n:55][cH:56][cH:57][cH:58][c:59]2[n:60][n:61]1>>[CH:1]1([N:4]([C:5](=[O:6])[c:7]2[cH:8][c:9]3[c:10]([n:11][c:12]([NH:19][c:20]4[s:21][c:22]([CH3:28])[c:23]([C:25](=[O:26])[N:36]([CH3:35])[CH3:37])[n:24]4)[c:13]4[c:14]3[n:15]([CH3:18])[cH:16][n:17]4)[n:29]2[CH2:30][CH3:31])[CH:32]2[CH2:33][CH2:34]2)[CH2:2][CH2:3]1

Participants

6

Reactant 5

HCID 674DimethylamineHCID 6228DimethylformamideHCID 9886HexafluorophosphateHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 581806502-(7-(Dicyclopropylcarbamoyl)-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-4-ylamino)-5-methylthiazole-4-carboxylic acid

Product 1

HCID 581805982-(7-(dicyclopropylcarbamoyl)-6-ethyl-1-methyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-4-ylamino)-N,N,5-trimethylthiazole-4-carboxamide

Sources & evidence

ORD record
ord-981fa27332444bd8918423931ab4f56d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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