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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1950647Generated: October 31, 2026

HCID 57934253, compound → HCID 57934339, compound

https://huagongshe.com/reaction/1950647

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 57934253HCID 57934253—
ReactantHCID 66627623HCID 66627623—
ReactantHCID 66627950HCID 66627950—
ProductHCID 57934339HCID 5793433938.7%

Reaction Steps

Synthesized from pivalic acid (R)-6-(2-ethylamino-4-methoxyphenyl)-5,6,7,8-tetrahydronaphthalen-2-yl ester (100 mg) and 4-[2-(tert-butoxycarbonylmethylamino)-2-methylpropyl]benzoic acid (120 mg) according to an analogous synthetic method to Preparation Example 86, pivalic acid 6-{2-{{4-[2-(tert-butoxycarbonylmethylamino)-2-methylpropyl]benzoyl}ethylamino}-4-methoxyphenyl}-5,6,7,8-tetrahydronaphthalen-2-yl ester (97 mg) was used according to analogous synthetic method to the above-mentioned Example 215 and Example 337 to provide the title compound (48 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08399520B2
Source datasetuspto-grants-2013_03
ORD IDord-4e36f3dd76784868a70ecb4df861bf38
Source noteuspto-grants-2013_03