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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1950988Generated: November 3, 2026

2,4,6-Trimethylbenzoic acid → 2,4,6-Trimethyl-cis-N-(2-pyrrolidin-1-yl-cyclopentyl)-benzamide

https://huagongshe.com/reaction/1950988

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4,6-Trimethylbenzoic acidHCID 10194—
Reactantcis-2-Pyrrolidin-1-yl-cyclopentylamineHCID 30820884—
Product2,4,6-Trimethyl-cis-N-(2-pyrrolidin-1-yl-cyclopentyl)-benzamideHCID 66681765—

Reaction Steps

The title compound, white solid, MS: m/e=301.2 [(M+H)+], was prepared in accordance with the general method of example 5 from cis-2-pyrrolidin-1-yl-cyclopentylamine (intermediate Q) and 2,4,6-trimethylbenzoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08404673B2
Source datasetuspto-grants-2013_03
ORD IDord-c9969799a7cd4811855fbd8473ca9f74
Source noteuspto-grants-2013_03