HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Cyclopropyl-4-(trifluoromethyl)benzoic acid → N-((1SR,2RS)-2-Cyclopentylamino-cyclopentyl)-2-cyclopropyl-4-trifluoromethyl-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Cyclopropyl-4-(trifluoromethyl)benzoic acid | HCID 59438485 | — |
| Reactant | HCID 66681699 | HCID 66681699 | — |
| Product | N-((1SR,2RS)-2-Cyclopentylamino-cyclopentyl)-2-cyclopropyl-4-trifluoromethyl-benzamide | HCID 51000996 | — |
Reaction Steps
The title compound, brown oil, MS: m/e=381.4 [(M+H)+], was prepared in accordance with the general method of example 5 from (1RS,2SR)—N-cyclopentyl-cyclopentane-1,2-diamine (intermediate AE) and 2-cyclopropyl-4-trifluoromethyl-benzoic acid (intermediate K).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08404673B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-28a8b3ecd7294c24bea4a0222aabfbde |
| Source note | uspto-grants-2013_03 |