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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1950997Generated: October 29, 2026

cis-2-Pyrrolidin-1-yl-cyclopentylamine → 2-Isopropoxy-N-((1SR,2RS)-2-pyrrolidin-1-yl-cyclopentyl)-4-trifluoromethyl-benzamide

https://huagongshe.com/reaction/1950997

Reaction equation

Participants

RoleNameHCIDCharge
Reactantcis-2-Pyrrolidin-1-yl-cyclopentylamineHCID 30820884—
ReactantHCID 59438527HCID 59438527—
Product2-Isopropoxy-N-((1SR,2RS)-2-pyrrolidin-1-yl-cyclopentyl)-4-trifluoromethyl-benzamideHCID 66681410—

Reaction Steps

The title compound, light brown oil, MS: m/e=385.2 [(M+H)+], was prepared in accordance with the general method of example 5 from cis-2-pyrrolidin-1-yl-cyclopentylamine (intermediate Q) and 2-isopropoxy-4-trifluoromethyl-benzoic acid (intermediate AF).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08404673B2
Source datasetuspto-grants-2013_03
ORD IDord-7920f017e82a4c368ec2d76ca20c64bb
Source noteuspto-grants-2013_03