反应详情

A solution of [2-(5-Ethyl-oxazol-2-yl)-ethyl]-carbamic acid benzyl ester (step 3) (0.41 g, 1.49 mmol), 2M HCl (0.75 ml) in ethanol (40 ml) is stirred under hydrogen in the presence of 10% Pd on Carbon (0.041 g) for 5 hours. The reaction mixture is filtered and concentrated in vacuo to yield the titled compound. This is neutralised using triethylamine to produce 2-(5-ethyl-oxazol-2-yl)-ethylamine

1. filtrationThe reaction mixture is filtered
2. concentrationconcentrated in vacuo