HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → HCID 67200542, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | 1-(2-Chloropyridin-4-yl)propan-2-one | HCID 82653143 | — |
| Product | HCID 67200542 | HCID 67200542 | — |
Reaction Steps
A stirred solution of 1-(2-chloro-pyridin-4-yl)-propan-2-one (1.6 g, 9.47 mmol) in morpholine is heated to 105° C. for 3 days. The morpholine is removed in vacuo to yield the crude product. Purification by chromatography on silica, eluting with 1:1 ethyl acetate-hexane affords the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08404684B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-5e5460eddb18410a8811bd332c810bac |
| Source note | uspto-grants-2013_03 |