HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetylthiourea → 1-(2,6-Dimethylpyridin-4-yl)propan-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetylthiourea | HCID 2723593 | — |
| Reactant | N-Pyrazinylthiourea | HCID 2771013 | — |
| Reactant | HCID 11254215 | HCID 11254215 | — |
| Reactant | 1-(2,6-Dimethylpyridin-4-yl)propan-2-one | HCID 12521822 | — |
| Product | 1-(2,6-Dimethylpyridin-4-yl)propan-2-one | HCID 12521822 | — |
| Product | HCID 86610331 | HCID 86610331 | — |
Reaction Steps
The titled compound is prepared by an analogous procedure to (4-Methyl-5-pyridin-4-yl-thiazol-2-yl)-pyrazin-2-yl-amine (Example 1) by replacing 1-pyridin-4-yl-propan-2-one (1b) in this procedure with 1-(2,6-dimethyl-pyridin-4-yl)-propan-2-one and by replacing and pyrazin-2-yl-thiourea (1a) with N-acetylthiourea. 1-(2,6-dimethyl-pyridin-4-yl)-propan-2-one was prepared according to a method described in Tetrahedron Letters, Vol. 25, No. 5, pp 515-518, 1984. (Authors: Claude Erre et al.)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08404684B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-1118582b94ed499eb8952dd9ab18e9c6 |
| Source note | uspto-grants-2013_03 |