HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → HCID 86653055, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 1-(2-Chloropyridin-4-yl)propan-2-one | HCID 82653143 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 86653055 | HCID 86653055 | — |
Reaction Steps
Bromine (1.36 ml, 26 mmol) is added dropwise to a stirred solution of 1-(2-chloro-pyridin-4-yl)-propan-2-one (Example 2a, 5.0 g, 29.5 mmol) in dioxane (150 ml) over 45 minutes at 5-10° C. After 20 minutes at room temperature the solvent is removed in vacuo to afford the titled compound as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08404684B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-9fca1a9703ec44b0be613960b1bfb8f7 |
| Source note | uspto-grants-2013_03 |