Trifluoroacetic acid → 2-(3-Ethyl-1,2,4-oxadiazol-5-yl)ethan-1-amine

HRID 1951217노트

반응식

HRID 1951217 반응식
C(O)(C(F)(F)F)=O.C(OC(=O)[NH:14][CH2:15][CH2:16][C:17]1[O:21][N:20]=[C:19]([CH2:22][CH2:23]C)[N:18]=1)(C)(C)C>C(Cl)Cl>[CH2:22]([C:19]1[N:18]=[C:17]([CH2:16][CH2:15][NH2:14])[O:21][N:20]=1)[CH3:23]

참가 물질

4

반응물 2

HCID 6422Trifluoroacetic acidHCID 57466817[2-(3-Propyl-[1,2,4]oxadiazol-5-yl)-ethyl]-carbamic acid tert-butyl ester

생성물 1

HCID 280631582-(3-Ethyl-1,2,4-oxadiazol-5-yl)ethan-1-amine

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

TFA (0.5 ml) is added to a stirred solution of [2-(3-propyl-[1,2,4]oxadiazol-5-yl)-ethyl]-carbamic acid tert-butyl ester (0.093 g, 0.39 mmol) in DCM (1 ml). After 1 hour the solvents are removed to afford the titled compound.

후처리

  1. customAfter 1 hour the solvents are removed

출처 및 근거

ORD 기록
ord-908363dd309d4ece87ff132d41c45960
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08404684B2

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