化工社化工社 化学情報印刷レポート · 研究参考用
Trifluoroacetic acid → 2-(3-Ethyl-1,2,4-oxadiazol-5-yl)ethan-1-amine
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Trifluoroacetic acid | HCID 6422 | — |
| 反応物 | [2-(3-Propyl-[1,2,4]oxadiazol-5-yl)-ethyl]-carbamic acid tert-butyl ester | HCID 57466817 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 2-(3-Ethyl-1,2,4-oxadiazol-5-yl)ethan-1-amine | HCID 28063158 | — |
反応手順
TFA (0.5 ml) is added to a stirred solution of [2-(3-propyl-[1,2,4]oxadiazol-5-yl)-ethyl]-carbamic acid tert-butyl ester (0.093 g, 0.39 mmol) in DCM (1 ml). After 1 hour the solvents are removed to afford the titled compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08404684B2 |
| 出典データセット | uspto-grants-2013_03 |
| ORD ID | ord-908363dd309d4ece87ff132d41c45960 |
| 出典メモ | uspto-grants-2013_03 |