Sodium Cyanide → HCID 11395772, compound

Participants

Reaction Conditions

Reaction Steps

Sodium cyanide (0.069 g, 1.4 mmol) is added to a stirred solution of 1-[2-(1-isopropyl-1H-imidazol-4-yl)-ethyl]-3-[5-(2-methanesulfonyl-6-methyl-pyrimidin-4-yl)-4-methyl-thiazol-2-yl]-urea (0.21 g, 0.47 mmol) in dry DMSO (10 ml). The reaction is stirred at 50° C. under argon for 3 hours then the solvent is removed. The residue is dissolved in DCM and washed with water. The organic extract is dried (MgSO4) and the solvent removed to give the titled compound.

Provenance & Evidence