HCID 46205404, compound → HCID 46205728, compound

HRID 1951322Notes

Reaction equation

HRID 1951322 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:9]2[N:10]=[C:11]3[C:16]([C:17](OCC)=[O:18])=[CH:15][CH:14]=[CH:13][N:12]3[CH:22]=2)[CH:6]=[CH:7][CH:8]=1>C(Cl)(Cl)(Cl)Cl>[OH:18][CH2:17][C:16]1[C:11]2[N:12]([CH:22]=[C:9]([C:5]3[CH:6]=[CH:7][CH:8]=[C:3]([O:2][CH3:1])[CH:4]=3)[N:10]=2)[CH:13]=[CH:14][CH:15]=1

Participants

3

Reactant 1

HCID 46205404HCID 46205404, compound

Product 1

HCID 46205728HCID 46205728, compound

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

From 2d (yield: 83%) as an oil; IR (CCl4) 2956, 1550, 1253 cm−1; 1H NMR (400 MHz, CDCl3) δ 3.89 (s, 3H), 5.05 (s, 2H), 6.74 (t, 1H, J=7 Hz), 6.89 (dd, 1H, J=2.5, 8 Hz), 7.06 (d, 1H, J=7 Hz), 7.34 (t, 1H, J=8 Hz), 7.51 (d, 1H, J=8 Hz), 7.54 (d, 1H, J=2.5 Hz), 7.83 (s, 1H), 8.03 (d, 1H, J=7 Hz); 13C NMR (100 MHz, CDCl3) δ 55.4, 62.6, 108.4, 111.4, 112.4, 113.9, 118.6, 121.4, 124.6, 129.7, 129.8, 134.9, 144.6, 144.9, 160.0; MS m/z 254 (M+, 58), 253 (100), 238 (12), 225 (22), 210 (16).

Sources & evidence

ORD record
ord-ed3d8fda9e4b48cbb4dce4d03fe15297
Source dataset
uspto-grants-2013_03
Patent number
US08404707B2

Reaction notes

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