Potassium Bromide → HCID 46205730, compound

HRID 1951324Notes

Reaction equation

HRID 1951324 reaction equation
[CH:1]([C:4]1[N:5]=[C:6]2[C:11]([C:12](OCC)=[O:13])=[CH:10][CH:9]=[CH:8][N:7]2[CH:17]=1)([CH3:3])[CH3:2].[K+].[Br-]>>[OH:13][CH2:12][C:11]1[C:6]2[N:7]([CH:17]=[C:4]([CH:1]([CH3:3])[CH3:2])[N:5]=2)[CH:8]=[CH:9][CH:10]=1

Participants

3

Reactant 2

HCID 253877Potassium BromideHCID 46205406HCID 46205406, compound

Product 1

HCID 46205730HCID 46205730, compound

Procedure

From 2f (yield: 47%); mp 97-99° C.; IR (KBr) 3250-3000, 2960, 1498, 1307 cm−1; 1H NMR (400 MHz, CDCl3) δ 1.30 (d, 6H, J=7 Hz), 3.06 (sept, 1H, J=7 Hz), 4.99 (s, 2H), 6.65 (t, 1H, J=7 Hz), 7.07 (d, 1H, J=7 Hz), 7.27 (s, 1H), 7.92 (d, 1H, J=7 Hz); 13C NMR (100 MHz, CDCl3) δ 22.5, 28.3, 62.6, 107.5, 111.8, 121.5, 124.4, 129.3, 143.7, 153.3; MS m/z 190 (M+, 43), 189 (100), 161 (25), 157 (23), 78 (15).

Sources & evidence

ORD record
ord-37abeb4477664cdd93da3ced0eead011
Source dataset
uspto-grants-2013_03
Patent number
US08404707B2

Reaction notes

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