HCID 46205727, compound → HCID 46205731, compound

HRID 1951325Notes

Reaction equation

HRID 1951325 reaction equation
[C:1]([C:5]1[N:6]=[C:7]2[C:12]([C:13](OCC)=[O:14])=[CH:11][CH:10]=[CH:9][N:8]2[CH:18]=1)([CH3:4])([CH3:3])[CH3:2]>C(Cl)(Cl)(Cl)Cl>[C:1]([C:5]1[N:6]=[C:7]2[C:12]([CH2:13][OH:14])=[CH:11][CH:10]=[CH:9][N:8]2[CH:18]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 1

HCID 46205727HCID 46205727, compound

Product 1

HCID 46205731HCID 46205731, compound

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

From 2g (yield: 52%) as an oil; IR (CCl4) 2962, 1498 cm−1; 1H NMR (400 MHz, CDCl3) δ 1.09 (s, 9H), 4.72 (s, 2H), 5.01 (s, 1H), 6.39 (t, 1H, J=7 Hz), 6.73 (d, 1H, J=7 Hz), 7.03 (s, 1H), 7.67 (d, 1H, J=7 Hz); 13C NMR (100 MHz, CDCl3) δ 30.1, 32.2, 62.4, 106.8, 111.6, 124.4, 129.1, 143.9, 156.4; MS m/z 204 (M+, 53), 203 (100), 175 (24), 171 (55).

Sources & evidence

ORD record
ord-46da9df358d149eeba1f3bb1924e7f4a
Source dataset
uspto-grants-2013_03
Patent number
US08404707B2

Reaction notes

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