Potassium Bromide → HCID 46206056, compound

HRID 1951333Notes

Reaction equation

[C:1]([C:5]1[N:6]=[C:7]2[C:12]([CH2:13][OH:14])=[CH:11][CH:10]=[CH:9][N:8]2[CH:15]=1)([CH3:4])([CH3:3])[CH3:2].[K+].[Br-]>>[C:1]([C:5]1[N:6]=[C:7]2[C:12]([CH:13]=[O:14])=[CH:11][CH:10]=[CH:9][N:8]2[CH:15]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

Reactant 2

HCID 253877Potassium Bromide

HCID 46205731HCID 46205731, compound

Product 1

HCID 46206056HCID 46206056, compoundYield 77%

Procedure

From 3g: reaction time 4 h (yield: 77%); mp 60-62° C.; IR (KBr) 1685, 1541, 1499 cm−1; 1H NMR (400 MHz, CDCl3) δ 1.43 (s, 9H), 6.86 (t, 1H, J=7 Hz), 7.46 (s, 1H), 7.76 (d, 1H, J=7 Hz), 8.28 (d, 1H, J=7 Hz), 10.85 (s, 1H); 13C NMR (100 MHz, CDCl3) δ 30.2, 32.7, 107.3, 111.1, 123.5, 124.5, 130.2, 144.2, 159.0, 189.6; MS m/z 202 (M+, 46), 187 (100), 174 (70), 78 (13).

Sources & evidence

ORD record: ord-0c93066c3ee14407b9ae3b12cf67f69e
Source dataset: uspto-grants-2013_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08404707B2

Reaction notes

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