HCID 46205398, compound → HCID 46205399, compound

HRID 1951334Notes

Reaction equation

HRID 1951334 reaction equation
[CH2:1]([O:3][CH:4]([O:16][CH2:17][CH3:18])[C:5]1[N:6]=[C:7]2[C:12]([CH2:13][OH:14])=[CH:11][CH:10]=[CH:9][N:8]2[CH:15]=1)[CH3:2]>C(Cl)(Cl)(Cl)Cl>[CH2:1]([O:3][CH:4]([O:16][CH2:17][CH3:18])[C:5]1[N:6]=[C:7]2[C:12]([CH:13]=[O:14])=[CH:11][CH:10]=[CH:9][N:8]2[CH:15]=1)[CH3:2]

Participants

3

Reactant 1

HCID 46205398HCID 46205398, compound

Product 1

HCID 46205399HCID 46205399, compoundYield 98%

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

From 3i: reaction time 15 h (yield: 98%) as an oil; IR (CCl4) 1693, 1056 cm−1; 1H NMR (400 MHz, CDCl3) δ 1.30 (t, 6H, J=7 Hz), 3.73 (m, 4H), 5.79 (s, 1H), 6.96 (t, 1H, J=7 Hz), 7.80 (s, 1H), 7.83 (d, 1H, J=7 Hz), 8.34 (d, 1H, J=7 Hz), 10.82 (s, 1H); 13C NMR (100 MHz, CDCl3) δ 15.3, 62.0, 98.6, 111.0, 112.0, 124.1, 125.7, 130.6, 144.1, 146.8, 189.1; MS m/z 248 (M+, 1), 204 (17), 175 (100).

Sources & evidence

ORD record
ord-d6018fb261394d0d94d95a31e3b7b1bb
Source dataset
uspto-grants-2013_03
Patent number
US08404707B2

Reaction notes

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