Hydrochloric Acid → HCID 68691867, compound

Participants

Reaction Steps

Concentrated hydrochloric acid (0.5 ml) was added to a solution of (8-allyl-1,4-dioxaspiro[4.5]dec-8-yl)-(4-methoxybenzyl)amine (C-9) (1.0 g, 3.15 mmol) in acetone (10 ml) and water (0.5 liter), and the mixture was stirred for 16 h at room temperature. Then saturated sodium hydrogen carbonate solution (40 ml) was added to the solution, and extraction with dichloromethane (3×40 ml) was carried out. The combined organic phases were dried with sodium sulfate and concentrated in vacuo.

Provenance & Evidence