反应详情

5-{4-[2-(4′-Bromo-biphenyl-4-ylmethyl)-4-(2,4-dichloro-phenyl)-imidazol-1-yl]-phenyl}1,2,5-thiadiazolidine-3-one-1,1-dioxide (67 mg, 0.1 mmol) was treated as described in general procedure R using excess 1-methylpiperazine (100 mg, 1 mmol) to give 5-(4-{4-(2,4-dichloro-phenyl)-2-[4′-(4-methyl-piperazin-1-yl)-biphenyl-4-ylmethyl]-imidazol-1-yl}-phenyl)-1,2,5-thiadiazolidine-3-one-1,1-dioxide.