Hydrochloric Acid → HCID 178421805, compound

HRID 1952283Notes

Reaction equation

HRID 1952283 reaction equation
C[O:2][C:3]1[C:16](=[O:17])[C:15]2[C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[C:8]([CH3:18])=[CH:7][C:6]=2[C:5](=[O:19])[CH:4]=1.[OH-].[Na+].Cl>CO>[OH:2][C:3]1[C:16](=[O:17])[C:15]2[C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[C:8]([CH3:18])=[CH:7][C:6]=2[C:5](=[O:19])[CH:4]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 68601851HCID 68601851, compound

Product 1

HCID 178421805HCID 178421805, compoundYield 30.8%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

3-Methoxy-9-methyl-1,4-phenanthrenequinone (1.17 g, 4.63 mM) was dissolved in 40 ml of methanol solution containing 5% NaOH, and the resulting solution was vigorously stirred at room temperature for 1 hour. The reaction solution was neutralized by 1N HCl and was then concentrated by distillation under reduced pressure. The resulting purified by chromatography to give 0.34 g (1.42 mM) of 3-Hydroxy-9-methyl-1,4-phenanthrenequinone.

Workup

  1. concentrationwas then concentrated by distillation under reduced pressure
  2. customThe resulting purified by chromatography

Sources & evidence

ORD record
ord-37e380b273b14b42a587bc6e53d97f38
Source dataset
uspto-grants-2013_03
Patent number
US08404869B2

Reaction notes

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