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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1952583Generated: November 2, 2026

Trifluoroacetic acid → HCID 86671260, compound

https://huagongshe.com/reaction/1952583

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 68226430HCID 68226430—
SolventDichloromethaneHCID 6344—
ProductHCID 86671260HCID 86671260—

Reaction Steps

To a solution of (S)-3-tert-Butoxycarbonylamino-2-{[5-(3-hydroxy-benzylcarbamoyl)-3-trifluoromethyl-thiophene-2-carbonyl]-amino}-propionic acid methyl ester (0.19 g, 0.34 mmol) in DCM (6 mL) was added TFA (3.0 mL). The mixture was stirred at room temperature 1 h and evaporated. Isolate 0.23 g of crude product which was used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08404859B2
Source datasetuspto-grants-2013_03
ORD IDord-82aef08293c046f8b7eacbf97139e019
Source noteuspto-grants-2013_03