反应详情

4,4-Diethoxy-1-phenyl-but-2-yn-1-ol (9.46 g, 40.38 mmol) was dissolved in dichloromethane (200 ml) and treated with activated MnO2 (100 g) at rt for 15 h. The reaction mixture was filtered through a plug of celite and Na2SO4. The filtrated was concentrated under reduced pressure to afford the desired ketone (7.85 g, 84% yield).

1. filtrationThe reaction mixture was filtered through a plug of celite and Na2SO4
2. concentrationThe filtrated was concentrated under reduced pressure