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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1952603Generated: November 3, 2026

Trifluoroacetic acid → HCID 86671262, compound

https://huagongshe.com/reaction/1952603

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 68226516HCID 68226516—
SolventDichloromethaneHCID 6344—
ProductHCID 86671262HCID 86671262—

Reaction Steps

To a solution of (S)-3-tert-Butoxycarbonylamino-2-({5-[(2-oxo-2,3-dihydro-1H-indol-4-ylmethyl)-carbamoyl]-3-trifluoromethyl-thiophene-2-carbonyl}-amino)-propionic acid methyl ester (0.10 g, 0.17 mmol) in DCM (5 mL) was added TFA (1.5 mL). The mixture was stirred at room temperature 1 h and evaporated. Isolate 0.14 g of crude product which was used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08404859B2
Source datasetuspto-grants-2013_03
ORD IDord-7b245f3429b54ffaa0528bc0401f6070
Source noteuspto-grants-2013_03