HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 86671262, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 68226516 | HCID 68226516 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 86671262 | HCID 86671262 | — |
Reaction Steps
To a solution of (S)-3-tert-Butoxycarbonylamino-2-({5-[(2-oxo-2,3-dihydro-1H-indol-4-ylmethyl)-carbamoyl]-3-trifluoromethyl-thiophene-2-carbonyl}-amino)-propionic acid methyl ester (0.10 g, 0.17 mmol) in DCM (5 mL) was added TFA (1.5 mL). The mixture was stirred at room temperature 1 h and evaporated. Isolate 0.14 g of crude product which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08404859B2 |
| Source dataset | uspto-grants-2013_03 |
| ORD ID | ord-7b245f3429b54ffaa0528bc0401f6070 |
| Source note | uspto-grants-2013_03 |