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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1952606Generated: November 1, 2026

Trifluoroacetic acid → HCID 68226469, compound

https://huagongshe.com/reaction/1952606

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 68226560HCID 68226560—
SolventDichloromethaneHCID 6344—
ProductHCID 68226469HCID 68226469—

Reaction Steps

To a solution of (S)-3-tert-Butoxycarbonylamino-2-({3-chloro-5-[(1H-indazol-4-ylmethyl)-carbamoyl]-thiophene-2-carbonyl}-amino)-propionic acid methyl ester (0.1015 g, 0.19 mmol) in DCM (5 mL) was added TFA (1 mL). The mixture was stirred at room temperature 2 h and evaporated. Isolate 0.127 g of crude product which was used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08404859B2
Source datasetuspto-grants-2013_03
ORD IDord-7eb4ebdddcda472ab927ba7f2942f9b9
Source noteuspto-grants-2013_03