Acetic Acid → Hydrazine, 1-formyl-2-phenyl-

HRID 1952765Notes

Reaction equation

HRID 1952765 reaction equation
[C:1]1([NH:7][NH2:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:9](O)(=[O:11])C.C(N)=O>O>[C:1]1([NH:7][NH:8][CH:9]=[O:11])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 176Acetic AcidHCID 713FormamideHCID 7516Phenylhydrazine

Product 1

HCID 12154Hydrazine, 1-formyl-2-phenyl-

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Phenylhydrazine (75 g) was added dropwise at <20° C. to stirred acetic acid (198 ml). When the addition was complete, formamide (27.9 ml) was added in one portion, and the mixture was stirred at ambient temperature for 4 hours. Water (225 ml) was added, and the resulting solid was collected by filtration, washed well with water, and dried in vacuo to give N'-phenylformohydrazide (68.8 g) as a cream solid, m.p. 138-143° C.

Workup

  1. additionWhen the addition
  2. filtrationthe resulting solid was collected by filtration
  3. washwashed well with water
  4. customdried in vacuo

Sources & evidence

ORD record
ord-a9577aca3c3546ab9215bcbcaafc12a3
Source dataset
uspto-grants-2000_09
Patent number
US06114334

Reaction notes

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