HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 131721967, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | 1,2-Pyrrolidinedicarboxylic acid, 5-oxo-, 1-(1,1-dimethylethyl) ester, (2S)- | HCID 104412 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 131721967 | HCID 131721967 | — |
Reaction Steps
N-Boc-Pyr-OH (5 g, 23.45 mmol) was dissolved in MeOH (50 ml), and HCl in dioxane (4N, 30 ml) was added. After refluxing for 12 h, the solvent was removed in a rotary evaporator and H-Pyr-OMe hydrochloride was obtained as product. Yield: 3.84 g (100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06114358 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-d799be9a3a4948f4a2db49d04e5bc6c1 |
| Source note | uspto-grants-2000_09 |