HRID1952991

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F

HCID2733207

O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate

C11H16BF4N5O

HCID15480559

未命名化合物

结构：NC(=N[N+](=O)[O-])NCCC[C@@H](NC(=O)C(c1ccccc1)c1ccccc1)C(=O)O

HCID136381100

未命名化合物

PRODUCTS

生成物

结构：NC(=O)NCc1cccc(CNC(=O)[C@@H](CCCNC(N)=N[N+](=O)[O-])NC(=O)C(c2ccccc2)c2ccccc2)c1

HCID136333684

未命名化合物

收率 50%

PROCEDURE

实验过程

Prepared analogously to Example 4b) from (R)-N5 -[amino(nitroimino]methyl]-N2 -(diphenylacetyl)-ornithine, 3-(amino-carbonylaminomethyl)benzenemethanamine and TBTU in a yield of 50% of theory. Colourless amorphous substance.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-58e7e5223fbb4a78a445579423555b38
来源数据集: uspto-grants-2000_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06114390
来源说明: uspto-grants-2000_09

反应 SMILES

[NH2:1][C:2](=[N:27][N+:28]([O-:30])=[O:29])[NH:3][CH2:4][CH2:5][CH2:6][C@H:7]([C:24](O)=[O:25])[NH:8][C:9](=[O:23])[CH:10]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.[NH2:31][C:32]([NH:34][CH2:35][C:36]1[CH:37]=[C:38]([CH2:42][NH2:43])[CH:39]=[CH:40][CH:41]=1)=[O:33].CN(C(ON1N=NC2C=CC=CC1=2)=[N+](C)C)C.[B-](F)(F)(F)F>>[NH2:31][C:32]([NH:34][CH2:35][C:36]1[CH:37]=[C:38]([CH2:42][NH:43][C:24](=[O:25])[C@@H:7]([CH2:6][CH2:5][CH2:4][NH:3][C:2]([NH2:1])=[N:27][N+:28]([O-:30])=[O:29])[NH:8][C:9](=[O:23])[CH:10]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:39]=[CH:40][CH:41]=1)=[O:33]