HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-(2-(Aminocarbonyl)ethyl]benzenemethanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 3-(4-Cyanophenyl)propanamide | HCID 23301767 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 4-(2-(Aminocarbonyl)ethyl]benzenemethanamine | HCID 23301859 | 88% |
Reaction Steps
Prepared analogously to Example 43b) from 4-cyanobenzenepropanamide by catalytic hydrogenation using palladium/activated charcoal and in the presence of 1 equivalent of 2N hydrochloric acid in a yield of 88% of theory. Colourless crystals (diethylether).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06114390 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-f29a4f9bbb4b437a946660ba3f8f408e |
| Source note | uspto-grants-2000_09 |