Ammonia → HCID 23301966, compound

HRID 1953038Notes

Reaction equation

HRID 1953038 reaction equation
[CH3:1][N:2]([CH3:18])[CH2:3][CH2:4][CH2:5][NH:6][C:7]([CH2:9][C:10]1[CH:17]=[CH:16][C:13]([C:14]#[N:15])=[CH:12][CH:11]=1)=[O:8].N>[Ni]>[CH3:18][N:2]([CH3:1])[CH2:3][CH2:4][CH2:5][NH:6][C:7]([CH2:9][C:10]1[CH:17]=[CH:16][C:13]([CH2:14][NH2:15])=[CH:12][CH:11]=1)=[O:8]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 23301852HCID 23301852, compound

Product 1

HCID 23301966HCID 23301966, compound

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

Prepared analogously to Example 6c) from 4-[[[[3-(dimethylamino)propyl]amino]carbonyl]methyl]benzonitrile by catalytic hydrogenation in the presence of Raney nickel and ammonia in a quantitative yield. Colourless, highly viscous oil, which was used in the next step without purification.

Workup

  1. customColourless, highly viscous oil, which was used in the next step without purification

Sources & evidence

ORD record
ord-e931fbe726b64770aea304a60a7a8b34
Source dataset
uspto-grants-2000_09
Patent number
US06114390

Reaction notes

Loading…