4-Chloro-3-nitrobenzoic acid → 4-Chloro-3-nitrobenzoyl chloride

HRID 1953246Notes

Reaction equation

HRID 1953246 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](O)=[O:7])=[CH:4][C:3]=1[N+:11]([O-:13])=[O:12].S(Cl)([Cl:16])=O>CN(C)C=O>[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([Cl:16])=[O:7])=[CH:4][C:3]=1[N+:11]([O-:13])=[O:12]

Participants

4

Reactant 2

HCID 73204-Chloro-3-nitrobenzoic acidHCID 24386Thionyl Chloride

Product 1

HCID 1234774-Chloro-3-nitrobenzoyl chloride

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideCatalyst

Procedure

20.1 g (0.1 mol) of 4-chloro-3-nitro-benzoic acid, 11 ml thionyl chloride and 1 drop of dimethylformamide are mixed together and refluxed for two hours. The thionyl chloride is evaporated off.

Workup

  1. temperaturerefluxed for two hours
  2. customThe thionyl chloride is evaporated off

Sources & evidence

ORD record
ord-5dc9b19c53684cd1aa4c357704dde878
Source dataset
uspto-grants-2000_09
Patent number
US06114532

Reaction notes

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