HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Morpholinecarbonyl chloride → 1-(Morpholine-4-carboxamido)cyclohexanecarboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Morpholinecarbonyl chloride | HCID 84810 | — |
| Reactant | Ethyl 1-aminocyclohexane-1-carboxylate hydrochloride | HCID 11241228 | — |
| Product | 1-(Morpholine-4-carboxamido)cyclohexanecarboxylic acid | HCID 11507137 | 33.4% |
Reaction Steps
The same reaction procedure as used in Reference Example 4 was repeated by using 4.36 g (21 mmol) of ethyl 1-aminocyclohexanecarboxylate hydrochloride and 3.15 g (21 mmol) of morpholine carbonyl chloride, whereby 1.8 g of the captioned 1-[N-(morpholine-4-carbonyl)amino]cyclohexanecarboxylic acid was obtained in a yield of 33%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06117870 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-1d2032a1737042ca882b5c0444386f18 |
| Source note | uspto-grants-2000_09 |