HCID 23298247, compound → HCID 23298248, compound

HRID 1953459Notes

Reaction equation

HRID 1953459 reaction equation
[Cl:1][CH2:2][CH2:3][S:4]([C:7]1[CH:12]=[C:11]([CH3:13])[N:10]([CH2:14][C:15]([O:17][CH2:18][CH3:19])=[O:16])[C:9](=[O:20])[C:8]=1[N+:21]([O-])=O)(=[O:6])=[O:5]>C(O)C.[Pt](=O)=O>[NH2:21][C:8]1[C:9](=[O:20])[N:10]([CH2:14][C:15]([O:17][CH2:18][CH3:19])=[O:16])[C:11]([CH3:13])=[CH:12][C:7]=1[S:4]([CH2:3][CH2:2][Cl:1])(=[O:6])=[O:5]

Participants

4

Reactant 1

HCID 23298247HCID 23298247, compound

Product 1

HCID 23298248HCID 23298248, compound

Reagents, catalysts & solvents 2

HCID 345198Adams' catalystCatalystHCID 702EthanolSolvent

Procedure

A mixture of platinum (IV) oxide (24 mg) and 4-(2-chloroethylsulfonyl)-1-ethyloxycarbonylmethyl-6-methyl-3-nitro-2-pyridinone (120 mg, 0.33 mmol) in ethanol (3.0 mL) was stirred under hydrogen for 16 h. The reaction was filtered through celite and evaporated to give the title compound as a glass:

Workup

  1. filtrationThe reaction was filtered through celite
  2. customevaporated

Sources & evidence

ORD record
ord-39eb0ea7d3364c579726b700d8f7ba72
Source dataset
uspto-grants-2000_09
Patent number
US06117888

Reaction notes

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