m-Chloroperbenzoic acid → HCID 23296532, compound

HRID 1954398Notes

Reaction equation

HRID 1954398 reaction equation
[C:1]1(=[O:23])[N:5]([C:6]2[CH:15]=[C:14]3[C:9]([C:10]([CH3:17])=[CH:11][C:12]([CH3:16])=[N:13]3)=[CH:8][CH:7]=2)[C:4](=[O:18])[C:3]2=[CH:19][CH:20]=[CH:21][CH:22]=[C:2]12.ClC1C=CC=C(C(OO)=[O:32])C=1>C(Cl)Cl>[C:4]1(=[O:18])[N:5]([C:6]2[CH:15]=[C:14]3[C:9]([C:10]([CH3:17])=[CH:11][C:12]([CH3:16])=[N+:13]3[O-:32])=[CH:8][CH:7]=2)[C:1](=[O:23])[C:2]2=[CH:22][CH:21]=[CH:20][CH:19]=[C:3]12

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 23296593HCID 23296593, compound

Product 1

HCID 23296532HCID 23296532, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

4.25 g (14 mmol) of 7-phthalimido-2,4-dimethyl-quinoline are dissolved in 500 ml of boiling methylene chloride. After cooling to ambient temperature, 4.80 g of 3-chloroperbenzoic acid (about 50% strength) are added. After 3 hours at ambient temperature the reaction solution is washed 1 x with sodium hydrogen carbonate solution and saline solution, dried over sodium sulphate, concentrated by evaporation and recrystallised from ethanol.

Workup

  1. washAfter 3 hours at ambient temperature the reaction solution is washed 1 x with sodium hydrogen carbonate solution and saline solution
  2. dry with materialdried over sodium sulphate
  3. concentrationconcentrated by evaporation
  4. customrecrystallised from ethanol

Sources & evidence

ORD record
ord-558ebce2ee824cdfb442abdc8954022d
Source dataset
uspto-grants-2000_09
Patent number
US06121308

Reaction notes

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