HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-(Hydroxymethyl)-5-nitrophenyl)ethanol → 2-(5-Amino-2-hydroxymethylphenyl)-ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-(Hydroxymethyl)-5-nitrophenyl)ethanol | HCID 10726586 | — |
| Catalyst | Platinum | HCID 23939 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-(5-Amino-2-hydroxymethylphenyl)-ethanol | HCID 23296182 | — |
Reaction Steps
Pt-C (50% water wet, 200 mg) was added to a THF (40 mL) solution of 2-(2-hydroxymethyl-5-nitrophenyl)-ethanol (1.0 g, 5 mmol) and the mixture was hydrogenated at 50 psi for 2 hrs. NMR showed complete reaction to form 2-(5-amino-2-hydroxymethyl-phenyl)-ethanol (compound (14) in Scheme 3).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06121283 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-09becfcd60114b08b4fe2e726a4482c7 |
| Source note | uspto-grants-2000_09 |