反应详情

Pt-C (50% water wet, 200 mg) was added to a THF (40 mL) solution of 2-(2-hydroxymethyl-5-nitrophenyl)-ethanol (1.0 g, 5 mmol) and the mixture was hydrogenated at 50 psi for 2 hrs. NMR showed complete reaction to form 2-(5-amino-2-hydroxymethyl-phenyl)-ethanol (compound (14) in Scheme 3).

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