Sodium Iodide → HCID 15486992, compound

HRID 1954464Notes

Reaction equation

HRID 1954464 reaction equation
Cl[CH2:2][Si:3]([CH3:10])([CH3:9])[C:4]1[O:5][CH:6]=[CH:7][CH:8]=1.[I-:11].[Na+]>C(#N)C>[I:11][CH2:2][Si:3]([CH3:10])([CH3:9])[C:4]1[O:5][CH:6]=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 5238Sodium IodideHCID 10397285HCID 10397285, compound

Product 1

HCID 15486992HCID 15486992, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Combine chloromethyl(dimethyl)furylsilane (4.4 g, 23.1 mmol) obtained from Example 2, step (a) with acetonitrile (100 mL). Add sodium iodide (3.5 g, 23.1 mmol) and stir overnight under nitrogen. Filter the mixture and remove ~40 mL of solvent via distillation.

Workup

  1. filtrationFilter the mixture
  2. customremove ~40 mL of solvent
  3. distillationvia distillation

Sources & evidence

ORD record
ord-c9090ecc1a714863864f0811cbf46da6
Source dataset
uspto-grants-2000_09
Patent number
US06121463

Reaction notes

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