Tetrahydrofuran → 8-[6-(1-Azetidinyl)-3-pyridinyl]-1,4-dioxaspiro[4.5]decan-8-ol
Reaction equation
[CH2:17]1[CH2:18][O:19][C:20]2([CH2:21][CH2:22][C:23](=[O:26])[CH2:24][CH2:25]2)[O:27]1.[CH2:28]1[O:29][CH2:30][CH2:31][CH2:32]1.[CH3:12][CH2:13][CH2:14][CH2:15][Li:16].[N:1]1([c:5]2[n:6][cH:7][c:8]([Br:11])[cH:9][cH:10]2)[CH2:2][CH2:3][CH2:4]1>>[N:1]1([c:5]2[n:6][cH:7][c:8]([C:23]3([OH:26])[CH2:22][CH2:21][C:20]4([O:19][CH2:18][CH2:17][O:27]4)[CH2:25][CH2:24]3)[cH:9][cH:10]2)[CH2:2][CH2:3][CH2:4]1Participants
5
Sources & evidence
- ORD record
- ord-4cc5ef57da914d069c163bc237aaf4ca
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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