Oxalic Acid → HCID 70071484, compound

HRID 1954699Notes

Reaction equation

HRID 1954699 reaction equation
[N:1]1([CH2:8][C:9]2[CH:10]=[C:11]([CH:16]([C:28]3[CH:33]=[CH:32][C:31]([OH:34])=[C:30]([CH2:35][N:36]4[CH2:42][CH2:41][CH2:40][CH2:39][CH2:38][CH2:37]4)[CH:29]=3)[CH:17]([NH:19][C:20](=[O:27])[C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[CH3:18])[CH:12]=[CH:13][C:14]=2[OH:15])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[C:43]([OH:48])(=[O:47])[C:44]([OH:46])=[O:45].C(OCC)(=O)C>C(O)C>[C:43]([OH:48])(=[O:47])[C:44]([OH:46])=[O:45].[N:1]1([CH2:8][C:9]2[CH:10]=[C:11]([CH:16]([C:28]3[CH:33]=[CH:32][C:31]([OH:34])=[C:30]([CH2:35][N:36]4[CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42]4)[CH:29]=3)[CH:17]([NH:19][C:20](=[O:27])[C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)[CH3:18])[CH:12]=[CH:13][C:14]=2[OH:15])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

5

Reactant 3

HCID 971Oxalic AcidHCID 8857Ethyl AcetateHCID 44460792HCID 44460792, compound

Product 1

HCID 70071484HCID 70071484, compoundYield 30%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

a solution of the product from Example 18 (0.28 g, 0.49 mmol) and oxalic acid (0.13 g, 1.02 mmol) in 5 mL ethanol was triturated with ethyl acetate. The solid which formed was collected by filtration and dried under vacuum at 75° C. to give the title compound (0.097 g, 25%) as a white solid.

Workup

  1. customThe solid which formed
  2. filtrationwas collected by filtration
  3. customdried under vacuum at 75° C.

Sources & evidence

ORD record
ord-ecfd68b3f99a405f823a52ee9bc48f9f
Source dataset
uspto-grants-2000_09
Patent number
US06124280

Reaction notes

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