1-Methylpiperazine → HCID 4327008, compound

Participants

Reaction Steps

By reaction of 4-chloroimidazo[1,2-a]quinoxaline (example 1) with N-methylpiperazine, according to a procedure that is similar to that followed in example 3, there is obtained 4-(N'-methylpiperazinyl)imidazo[1,2-a] quinoxaline. m.p. (DSC)=305.6° C.(onset); IR (KBr): 2697, 1560, 1508 cm-1 ; 1H-NMR (DMSO-d6 /CD3OD): δ8.7 (1H,sb), 8.3÷8.0 (1H,m), 7.8÷7.35 (4H,m), 5.5 (4H,t), 3.7÷3.3 (4H,m), 2.8 (3H,s); UV (EtOH): λmax =230, 291, 304, 320 nm. Elementary analysis for C15H17N5.2HCl (m.w. 340.25): calcd. C 52.95, H 5.63, N 20.58%; found C 52.81, H 5.78, N 20.13%.

Provenance & Evidence