1-Methylpiperazine → HCID 4327008, compound

HRID 1954715Notes

Reaction equation

HRID 1954715 reaction equation
Cl[C:2]1[C:3]2[N:4]([CH:12]=[CH:13][N:14]=2)[C:5]2[C:10]([N:11]=1)=[CH:9][CH:8]=[CH:7][CH:6]=2.[CH3:15][N:16]1[CH2:21][CH2:20][NH:19][CH2:18][CH2:17]1>>[CH3:15][N:16]1[CH2:21][CH2:20][N:19]([C:2]2[C:3]3[N:4]([CH:12]=[CH:13][N:14]=3)[C:5]3[C:10]([N:11]=2)=[CH:9][CH:8]=[CH:7][CH:6]=3)[CH2:18][CH2:17]1

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 107745254-chloroimidazo[1,2-a]quinoxaline

Product 1

HCID 4327008HCID 4327008, compound

Procedure

By reaction of 4-chloroimidazo[1,2-a]quinoxaline (example 1) with N-methylpiperazine, according to a procedure that is similar to that followed in example 3, there is obtained 4-(N'-methylpiperazinyl)imidazo[1,2-a] quinoxaline. m.p. (DSC)=305.6° C.(onset); IR (KBr): 2697, 1560, 1508 cm-1 ; 1H-NMR (DMSO-d6 /CD3OD): δ8.7 (1H,sb), 8.3÷8.0 (1H,m), 7.8÷7.35 (4H,m), 5.5 (4H,t), 3.7÷3.3 (4H,m), 2.8 (3H,s); UV (EtOH): λmax =230, 291, 304, 320 nm. Elementary analysis for C15H17N5.2HCl (m.w. 340.25): calcd. C 52.95, H 5.63, N 20.58%; found C 52.81, H 5.78, N 20.13%.

Sources & evidence

ORD record
ord-0a8c8a91ad6c4729aa13133129b40280
Source dataset
uspto-grants-2000_09
Patent number
US06124287

Reaction notes

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