Cyclohexylamine → HCID 10731766, compound

Participants

Reaction Steps

By reacting 4-chloro-8-fluoroimidazo[1,2-a] quinoxaline (example 25) with cyclohexylamine, following a procedure that is similar to that described in example 3, there is obtained 4-cyclohexylamino-8-fluoroimidazo[1,2-a]quinoxalin. m.p. (DSC)=157.6° C.(onset); IR (KBr): 3415, 2927, 1556 cm-1 ; 1H-NMR (CDCl3): δ7.8 (1H,dd, J=2 Hz), 7.7÷7.35 (1H,dd, JHF =16 Hz), 7.55 (1H,d, J=2 Hz), 7.55÷7.25 (1H,dd, JHF =16 Hz), 7.05 (1H,dd), 6.0 (1H,d), 4.25 (1H,m), 2.35÷1.2 (10H,m); UV (EtOH): λmax =226, 239, 285, 297, 323, 337 nm. Elementary analysis for C16H17FN4 (m.w. 284.33): calcd. C 67.59, H 6.03, N 19.71%; found C 67.31, H 6.04, N 19.70%.

Provenance & Evidence