HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodoethane → 2-(2,3-Dichlorophenyl)-3-ethoxy-4-fluoro-2-butenenitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodoethane | HCID 6340 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-(2,3-Dichlorophenyl)-4-fluoro-3-hydroxy-2-butenenitrile | HCID 70186294 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-(2,3-Dichlorophenyl)-3-ethoxy-4-fluoro-2-butenenitrile | HCID 54395328 | — |
Reaction Steps
Alkylation of 2-(2,3-dichlorophenyl)-4-fluoro-3-hydroxy-2-butenenitrile can suitably be achieved using ethyl iodide in dimethylformamide in the presence of potassium carbonate to afford crude 2-(2,3-dichlorophenyl)-3-ethoxy-4-fluoro-2-butenenitrile.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06124308 |
| Source dataset | uspto-grants-2000_09 |
| ORD ID | ord-6bda4592dbf4468898c206ced87ecc52 |
| Source note | uspto-grants-2000_09 |